Based on a request from the U.S. Geological Survey (USGS), we evaluated compliance with health and safety requirements at the Geological Survey TRIGA Reactor (GSTR) laboratory, located at the Federal Center in Lakewood, CO, from fiscal years 2013 to 2016. Nonpower reactors such as the GSTR are designed for research experiments on geologic, plant, and animal specimens. We found that USGS did not manage the GSTR laboratory in accordance with established health and safety regulations.